During the COVID-19 outbreak, researchers and medical experts around the world are working hard to develop clinically effective treatments for COVID-19 patients, such as the high-flow oxygen nasal cannula raised by artist Jia Yongjie. Moderate to severe patients are very important. In addition to this, there is also recent research evidence that nutritional supplements may help reduce viral load and hospitalization rates in COVID-19 patients.
Wu Changteng, the attending physician of the Department of Pediatric Emergency at Chang Gung Hospital in Linkou, pointed out on Facebook that there are still other virus variants that are spreading internationally, so the epidemic must not be taken lightly; and the role of vitamins and minerals in the COVID-19 battle is also Very important.
Wu Changteng explained that the new coronavirus (SARS-CoV-2) infection will have a significant impact on the immune system through a variety of inflammatory responses and cytokine storms, so foreign researchers have also turned their attention to methods to enhance the human immune system superior. When our body lacks vitamins and minerals in our blood, it can lead to poor immune system performance, which in turn can lead to a dysregulated immune state, even life-threatening!
A balanced intake of some common vitamins and minerals in daily life, including vitamins A, B, C, D, E and K, and micronutrients such as sodium, zinc, potassium, chloride, calcium and phosphorus, may Helps maintain our overall health and strengthen the immune system, thereby reducing infections.
Changteng Wu's abstract was recently published in InfIn a study in the journal Lammopharmacology, researchers review recent data on the role of vitamins and minerals in the treatment of patients with COVID-19; evidence suggests that vitamins act as immune boosters, and nutritional supplements may help reduce COVID-19 Viral load and hospitalization rates in patients. Vitamins have antioxidant properties and immunomodulatory effects, some of which regulate genes in immune cells, their expression, and help immune cells mature and differentiate.
Controls various genes involved in innate and adaptive immune responses.
Is critical to the normal physiological function of the body as they help the body utilize nutrients such as carbohydrates, proteins and fats.
is a coenzyme important for the function of the nervous and immune system and has anti-inflammatory properties, but its deficiency can affect the immune system, leading to increased inflammation and oxidative responses. Adequate levels of vitamin B1 can help boost immunity against the novel coronavirus as it eliminates the novel coronavirus by triggering both humoral and cell-mediated immunity.
is an immunomodulatory neuroactive compound that reduces pathogens in the blood of COVID-19 patients, thereby reducing the risk of transfusion transmission of COVID-19.
It has anti-inflammatory properties, and recent research suggests it can help reduce inflammation in COVID-19 patients, and it can even be used as an adjunctive therapy.
Affects innate, adaptive immunity and proliferation of immune cells. A recent study showed that vitamin B6 supplementation may alleviate COVID-19 symptoms by reducing pro-inflammatory cytokines, improving immune responses, and preventing hypercoagulable states.
It is essential for DNA and protein synthesis and plays an important role in the adaptive immune response. According to recent research, folic acid inhibits furin protease and blocks the binding of the novel coronavirus spike protein, which helps control the respiratory disease of COVID-19.
Regulates chemokine/cytokine formation and mediates communication between immune cells in pathophysiological pathways to protect against various bacterial and viral infections, including COVID-19.
Famous for antiviral properties such as increasing interferon-alpha production, regulating cytokines, reducing inflammation, improving endothelial dysfunction and restoring mitochondrial function, vitamin C supports the immune system in fighting bacterial and viral infections.
It has antioxidant and anti-inflammatory properties and can inhibit the overexpression of inflammatory cytokines IL-1α, IL-1β and tumor necrosis factor-α. According to research reports, it regulates the expression of ACE2 in lung tissue.
A potent antioxidant that plays an important role in regulating immune system function. Studies have shown that increasing vitamin E intake can help maintain immunity in older adults.
A fat-soluble vitamin that occurs naturally in certain foods and is aof coenzymes. Vitamin K1 is involved in the activation of hepatic coagulation factors, thus helping to combat thrombotic complications in COVID-19 patients.
In addition, Wu Changteng also mentioned that mineral supplements have been shown to have a positive impact on immunity against viral infections, and prevent and reduce cardiovascular and cerebrovascular diseases, which are characteristic of severe COVID-19 infections. Early COVID-19 research suggests that chronic mineral deficiencies may lead to elevated levels of ACE2 in cells of the lower respiratory tract, which in turn may increase the severity of infection.
Studies show that:
1. The sodium level of COVID-19 patients was significantly reduced.
2. Low potassium levels can lead to increased risk of ARDS (Acute Respiratory Distress Syndrome) and acute heart injury, common complications of COVID-19.
3. Calcium can eliminate the virus in cells, and reports show lower calcium concentrations in patients with severe COVID-19 compared to patients with milder disease.
4. Low phosphorus levels in severe COVID-19 patients, suggesting the importance of monitoring serum phosphorus levels in critical COVID-19 patients.
5. Magnesium is an oft-forgotten cation, and magnesium supplementation may help manage the stress of COVID-19 survivors and medical staff during the COVID-19 pandemic and PTSD; it also regulates various immune functions, and plays a crucial role in the immune response to viral infections.
6. Trace elements such as zinc, copper, manganese and selenium, also exhibits antiviral activity by inhibiting viral replication in host cells. "Zinc" can be used as an immunologically active agent against H1N1 influenza, and there is evidence that zinc supplementation reduces ACE2 activity in rat lungs. Therefore, zinc supplementation may be an adjunct therapy for COVID-19 treatment. In vitro data show that Zn2+ cations inhibit the replication of SARS-CoV-2 RNA polymerase by inhibiting its replication.
Summary, vitamin and micronutrient supplements may have a positive effect on COVID-19 prevention or treatment outcomes. However, Wu Changteng also reminded that we should pay attention to whether the intake of vitamins and minerals is sufficient, not to eat a lot, but not to consume as much as possible.
Documentation: Role of vitamins and minerals as immunity boosters in COVID-19 Inflammopharmacology (2021)
"Health 2.0" reminds you
In response to the new crown pneumonia epidemic, the CDC continues to strengthen epidemic monitoring and border control measures, and wear a mask as instructed to seek medical treatment as soon as possible, and actively inform the doctor of travel history and contact history, so as to facilitate timely Diagnosis and notification.
◎ Image source/Dazhi Image/Shutterstock ◎ Source / 543-Dr. Wu Changteng in Pediatric Emergency
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